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On the Zelenko protocol: The road not taken


Abstract: Dr. Vladimir Zev Zelenko proposed an early outpatient treatment for the SARS-CoV-2 pandemic in two letters dated March 24, 2020 and April 28, 2020, that were then followed up with a research publication dated December 2020. We introduce a mathematical technique for conducting rapid statistical analysis of observational data that can be used to make emergency decisions in the midst of a crisis, on whether to deploy new proposed treatments based on repurposed drugs. The technique is limited to the special case of repurposed drugs that have an known excellent safety record, and it can be used to rapidly establish whether the proposed treatment works, while leaving open the question of how well it works. Note: At this time, this is a non-peer reviewed preliminary research report.


Shorter introductory presentation for the general public -- April 2021


Extended 2-hour research presentation -- April 2021


Update concerning Dr. Didier Raoult's latest paper -- July 2021


Additional presentations

  1. H.A. Risch: Hydroxychloroquine and its friends
  2. P.A. McCullough: Pathophysiologic Basis and Clinical Rationale for Early Ambulatory Treatment for COVID-19 and Update on Vaccine Safety
  3. D. Raoult: Management of COVID-19 in Marseille Institute.
  4. J. Rose: VAERS UPDATE for CCCA (Canadian COVID Care Alliance)
  5. P.A. McCullough: "Therapeutic Nihilism And Untested Novel Therapies"
  6. J. Rose: Presentation of VAERS data to the World Council for Health

Disclaimer: This presentation does not necessarily represent the opinions or policies of the University of Texas -- Rio Grande Valley, but it is protected under Academic Freedom in Research and the 1st Amendmend of the United States Constitution.